Cancers, Vol. 12, Pages 224: JNK Pathway Mediates Low Oxygen Level Induced Epithelial –Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer Cells

Conclusions: This study suggests 10% O2 as another possible condition for EMT induction, and SM and JNK pathways play important roles in these processes through multiple factors. Inhibition of JNK could be explored as treatment for inhibiting metastasis in colorectal cancer cells.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research