Risk factors for delayed hemorrhage after endoscopic sphincterotomy
This study aimed to explore the risk factors for post-EST delayed hemorrhage and suggest some precautionary measures.MethodsThis study analyzed 8477 patients who successfully underwent endoscopic retrograde cholangiopancreatography (ERCP) and EST between January 2007 and June 2015 in the First Affiliated Hospital of Nanchang University. Univariate and multivariate analyses were performed to find the risk factors for delayed hemorrhage after EST.ResultsOf the 8477 patients screened, 137 (1.62%) experienced delayed hemorrhage. Univariate analysis showed that male, the severity of jaundice, duodenal papillary adenoma and carcinoma, diabetes, intraoperative bleeding, moderate and large incisions, and directional deviation of incision are risk factors for post-EST delayed hemorrhage (P
ConclusionsPatients with CMS were more likely to present with increased comorbidities. Patients with CMS undergoing CABG were at risk for worse short ‐term secondary postoperative outcomes and reduced long‐term survival. The data supports the need for further investigation for risk reduction surrounding operative revascularization.
ConclusionUA leads to disruption of Rac1 and Pak1 activity with subsequent actin depolymerization and migration. Thus, use of dietary UA in cancer prevention or as adjuvant therapy is promising.
Publication date: Available online 16 February 2020Source: The American Journal of SurgeryAuthor(s): Rachel L. Warner, K. Conley Coleman, Kelsey A. Musgrove, James M. Bardes, David C. Borgstrom, Daniel J. GraboAbstractBackgroundUse of minimally invasive techniques for management of common bile duct (CBD) stones has led to declining number of CBD explorations (CBDE) performed at teaching and non-teaching institutions. We evaluate the impact of this decline on surgery training in bile duct procedures.Study designNational operative data for general surgery residents (GSR) were examined from 2000 to 2018. Biliary operations in...
ConclusionsPositive FS analysis is a poor prognostic factor after PD for PDAC. It is significantly associated with a high rate of R1 resection at final histology, PDAC recurrence and poor survival.
Condition: Diabetes Mellitus Interventions: Other: Administration of standardized questionnaires; Device: Physical activity tracker; Other: Dietary log Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Recruiting
Conditions: Advanced Solid Tumors; MSI-H/dMMR Tumors; Cutaneous Squamous Cell Carcinoma; Urothelial Carcinoma, HCC; Cervical Cancer; Esophageal Squamous Cell Carcinoma; Merkel Cell Carcinoma, Small-cell Lung Cancer; Mesothelioma; PD-L1 Amplified Tumor (9p24.1); Nasopharyngeal Carcinoma; Cyclin-dependent Kinase 12 Mutated Tumors; Basal Cell Carcinoma (Unresectable or Metastatic); Sarcoma...
Condition: Diabetes Mellitus, Type 2 Interventions: Other: Mobile Application-Based Diabetes Education; Other: Health Coaching Sponsor: Indonesia University Active, not recruiting
Condition: Gestational Diabetes Mellitus Intervention: Behavioral: Low Glycemic Index Education Sponsors: IWK Health Centre; Mount Saint Vincent University; Dalhousie University; The Hospital for Sick Children Recruiting
Conditions: T2DM (Type 2 Diabetes Mellitus); Diet, Healthy; Renal Function Disorder; Albuminuria Intervention: Drug: Sulfa-zero: possible benefits of the treatment of new generation hypoglycaemic drugs compared to sulphonylureas Sponsor: University of Milan Recruiting
Condition: Hepatocellular Carcinoma Non-resectable Intervention: Combination Product: PD-1 mAb combined with TACE and lenvatinib Sponsor: Tianjin Medical University Cancer Institute and Hospital Recruiting