Colchicine Found Effective in Acute Pericarditis

Although colchicine has been shown to be beneficial in patients with recurrent pericarditis, which is thought to have a large inflammatory component related to an immune response, until now its efficacy in a first episode of acute pericarditis has been uncertain, as these episodes are thought to usually have a viral component that might benefit from an inflammatory response. In a study published in the New England Journal of Medicine, 240 patients with acute pericarditis and receiving conventional therapy with aspirin or ibuprofen were randomized to colchicine or placebo for 3 months. Colchicine was found effective in reducing the rate of incessant More…
Source: CardioBrief - Category: Cardiology Authors: Tags: Prevention, Epidemiology & Outcomes Acute pericarditis Colchicine inflammation The New England Journal of Medicine Source Type: blogs