MiR-195 inhibits migration, invasion and epithelial-mesenchymal transition (EMT) of endometrial carcinoma cells by targeting SOX4.

In conclusion, our study suggested that miR-195 inhibited the migration, invasion and epithelial mesenchymal transition (EMT) of EC cells at least partly by targeting SOX4. Our study provided a novel underlying mechanism for EC metastasis and a promising therapeutic target for EC management.
PMID: 31894127 [PubMed - in process]

Source: Journal of Biosciences - November 30, 2019 Category: Biomedical Science Authors: Zhao X, Dai L, Yue Q, Wang H, Wang XU, Li Y, Chen R Tags: J Biosci Source Type: research