Propofol pretreatment prevents oxygen-glucose deprivation/reoxygenation(OGD/R)-induced inflammation through nuclear transcription factor κB (NF-κB) pathway in neuroblastoma cells.

CONCLUSION: Our work demonstrated for the first time that propofol pretreatment ameliorated OGD/R induced inflammation via NF-κB pathway modulation in mouse neuroblastoma N2A cells, indicating propofol might be considered as a potential therapeutic approach to reduce inflammation in neuroblastoma. PMID: 31880261 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31880261?dopt=Abstract

Source: Current Neurovascular Research - December 25, 2019 Category: Neurology Authors: Hu F, Jiang J, Yu G, Zang H, Sun H Tags: Curr Neurovasc Res Source Type: research