Does the neuropsychiatric inventory predict progression from mild cognitive impairment to dementia? A systematic review and meta-analysis.
CONCLUSIONS: Our results suggest that NPI/NPI-Q ratings are associated with conversion from MCI to dementia. PMID: 31881368 [PubMed - as supplied by publisher]
The number of deaths from dementia and Alzheimer’s increased by more than 5,000 during the peak of the coronavirus pandemic, new stats have shown.
Conditions: Dementia; Caregiver Burnout Intervention: Combination Product: Alianza Latina Sponsors: University of Kansas Medical Center; National Institute on Minority Health and Health Disparities (NIMHD) Not yet recruiting
Conditions: Neurocognitive Disorders; Dementia; Cognitive Impairment; Cognitive Decline; Cognitive Dysfunction; Social Behavior Intervention: Behavioral: Cognitive Stimulation Sponsor: CEDIARA - Assoc. Solidariedade Social de Ribeira de Fráguas Not yet recruiting
This study is a cross-sectional analysis of the baseline data of 90 participants (age 77.1 [6.6] years, 43% female) from the FIT-AD trial. Cardiopulmonary exercise testing produced significantly higher peak heart rate (118.6 [17.5] vs. 106 [22.8] vs. 106 [18.8] beats/min), rating of perceived exertion (16 [2.1] vs. 12 [2.3] vs. 11 [2.1]), and systolic blood pressure (182 [23.7] vs. 156 [18.9] vs. 150 [16.9] mmHg) compared with the shuttle walk test and 6-min walk test, respectively. Peak walking distance on shuttle walk test (241.3 [127.3] m) and 6-min walk test (365.0 [107.9] m) significantly correlate...
CONCLUSIONS: Guilt is a relevant variable in understanding caregiver distress, and its analysis is necessary for therapeutic work in the field of care. CLINICAL IMPLICATIONS: Psychological interventions aimed at family caregivers should include specific techniques in order to address guilt feelings. PMID: 32496935 [PubMed - as supplied by publisher]
CONCLUSIONS: These themes synthesize the existing literature and produce a line of argument explaining the experience of children whose parents have YOD. CLINICAL IMPLICATIONS: Information and policies regarding YOD should take account of the experiences of patients' children and should include targeted support for children of parents with YOD. PMID: 32496888 [PubMed - as supplied by publisher]
Deaths due to dementia rose in the first two months of the pandemic, official figures show.
The current absence of a disease-modifying treatment for Alzheimer disease highlights the necessity for the benefits of nonpharmacological approaches. We aimed to investigate the effect of exercise in older patients with Alzheimer dementia. This is an observational, prospective cohort study in medical center. Eighty older patients with Alzheimer dementia, including 54 with mild dementia and 26 with moderate dementia, were followed up over 2 years. Patients were divided into exercise and no-exercise groups according to their weekly exercise habit. Mini-Mental State Examination (MMSE), clinical dementia rating (CDR), and se...
Publication date: Available online 3 June 2020Source: The Arts in PsychotherapyAuthor(s): Kevin Charras, Jean-Bernard Mabire, Nathalie Bouaziz, Peggy Deschamps, Bénédicte Froget, Adèle de Malherbe, Sara Rosa, Jean-Pierre Aquino
Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. However, other non-dopaminergic neuronal systems such as the serotonergic system are also involved. Serotonergic dysfunction is associated with non-motor symptoms and complications, including anxiety, depression, dementia, and sleep disturbances. This pathology reduces patient quality of life. Interaction between the serotonergic and other neurotransmitters systems such as dopamine, noradrenaline, glutamate, and GABA controls the activity of striatal neurons and are particularly interesting for understan...