Plasmodium falciparum histidine rich protein HRPII inhibits the antiinflammatory function of antithrombin.

CONCLUSION: We postulate that Pf-derived HRPII and polyphosphate can contribute to the pathogenesis of malaria infection by downregulating the AT-dependent antiinflammatory and anticoagulant pathways. PMID: 31858717 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31858717?dopt=Abstract

Source: Thrombosis and Haemostasis - December 18, 2019 Category: Hematology Authors: Dinarvand P, Yang L, Biswas I, Giri H, Rezaie AR Tags: J Thromb Haemost Source Type: research