Longevity protein SIRT6 also protects against fatty liver and fatty liver disease

(Bar-Ilan University) SIRT6 regulates fat metabolism by activating another protein called peroxisome proliferator-activated receptor alpha (PPAR-alpha). 'SIRT6 is like a juggler that coordinates between metabolic processes in the body,' says the study's lead author Prof. Haim Cohen. 'By working together with PPAR-alpha, SIRT6 can actually send a message to the body to burn more fat. This cooperation is one way in which SIRT6 protects against fatty liver and fatty liver disease, as well as obesity-related damage.'
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news