Serum Lactate and A Relative Change in Lactate as Predictors of Mortality in Patients With Cardiogenic Shock – Results from the Cardshock Study

Conclusion: The main findings of the present study are that baseline lactate is a powerful predictor of 30-day mortality, lactate at 6, 12, and 24 h after admission are predictors of 30-day mortality, and a relative change in lactate is a significant predictor of survival within the first 24 h after instituting intensive care treatment adding information beyond the information from baseline values.
Source: Shock - Category: Emergency Medicine Tags: Clinical Science Aspects Source Type: research

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There are limited data on the outcomes of acute myocardial infarction with cardiogenic shock (AMI-CS) in patients with prior coronary artery bypass grafting (CABG).
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Background: Thirty-day mortality in ST-elevation myocardial infarction (STEMI) patients is primarily driven by cardiogenic shock (CS). High neutrophil counts and high neutrophil/lymphocyte ratios (NLR) have previously been associated with mortality in STEMI patients; however, there is only sparse knowledge regarding their association with CS. Purpose: We sought to assess the associations between neutrophil count and NLR with the development of CS as well as 30-day mortality in STEMI patients. Methods: Patients admitted with STEMI at two tertiary Heart Centres throughout 1 year were included in the study and stratif...
Source: Shock - Category: Emergency Medicine Tags: Clinical Science Aspects Source Type: research
ConclusionsAcute qRBBB myocardial infarction is a sinister form of acute coronary syndrome which entails high in-hospital mortality and morbidity, necessitating early recognition and prompt institution of reperfusion therapy. Extreme deviation of QRS axis to the right [180-269 degrees] is a significant electrocardiographic predictor of in-hospital mortality.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Cardiogenic shock (CS) is the most serious complication of acute myocardial infarction (AMI). The practice of early revascularization by percutaneous coronary intervention, and advances in pharmacotherapy have reduced the rate of complications of CS. However, when CS is combined with AMI, mortality from AMI is still high, and many clinicians are wondering how to treat CS with AMI. In recent years, mechanical circulatory support (MCS) devices have improved the clinical outcome in AMI patients with CS. For best outcome, treatment of AMI with CS should always consider treatments that improve the prognosis of the patients.
Source: Heart Failure Clinics - Category: Cardiology Authors: Source Type: research
Since 1999, after the SHOCK trial demonstrated a reduction in mortality with early myocardial revascularization in patients with acute myocardial infarction complicated by cardiogenic shock, intensive care specialists and interventionalists have searched for additional ways to reduce the persistently high mortality, often in the range of 40% to 50%. After other reports demonstrated that intra-aortic balloon pump (IABP) support failed to reduce mortality, the next step was development and evaluation of other approaches for active mechanical circulatory support, including microaxial left ventricular assist devices (LVADs), i...
Source: JAMA - Journal of the American Medical Association - Category: General Medicine Source Type: research
Purpose of review Cardiogenic shock remains a complex clinical syndrome with high morbidity and mortality. The purpose of this article is to review important landmark trials as well as the relevant recent literature for percutaneous mechanical circulatory support following acute myocardial infarction. Recent findings The sole use of intraaortic balloon pumps for cardiogenic shock following acute myocardial infarction continues to be questioned with downgrading of its recommendation in recent years, there however may remain a role in patients with mechanical complications of their myocardial infarction. The combined us...
Source: Current Opinion in Cardiology - Category: Cardiology Tags: HEART FAILURE: Edited by Haissam Haddad Source Type: research
Simultaneous occlusion of two coronary arteries in acute MI is infrequent and may be accompanied by cardiogenic shock. Prompt restoration of normal coronary flow can salvage the myocardium and decrease a possible risk of death from complications. AbstractSimultaneous occlusion of two coronary arteries in acute MI is infrequent and may be accompanied by cardiogenic shock. Prompt restoration of normal coronary flow can salvage the myocardium and decrease a possible risk of death from complications.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
This study was designed to identify factors associated with unsuccessful weaning from venoarterial extracorporeal membrane oxygenation. METHODS: Data from 166 coronary artery bypass grafting patients supported with venoarterial extracorporeal membrane oxygenation at the Beijing Anzhen Hospital between February 2004 and March 2017 were retrospectively analyzed. Multivariable logistic regression was performed using bootstrapping methodology to identify factors independently associated with unsuccessful weaning from venoarterial extracorporeal membrane oxygenation. RESULTS: A total of 106 patients (64%) could be wea...
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
CONCLUSIONS: Short-term survival for patients with STEMI and OHCA undergoing emergent coronary angiography and revascularization with TTM in this contemporary, multicenter registry was high and neurologic outcome was good in more than half of patients. PMID: 31941835 [PubMed - as supplied by publisher]
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
ane B PMID: 31992453 [PubMed - as supplied by publisher]
Source: Therapie - Category: Psychiatry & Psychology Authors: Tags: Therapie Source Type: research
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