Evaluation of immunoinhibitory checkpoints in oral osteosarcomas

Cancers have been categorized into 4 different tumor microenvironments (TME) based on the presence of PD-L1 expression and tumor-infiltrating lymphocytes (TIL). However, oral osteosarcoma (OO) has not yet been studied. This research evaluated the immunoexpression of PD-L1 and TIL CD8+ and PD-1+ in a series of cases of OO.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - December 15, 2019 Category: ENT & OMF Authors: ALINE CARVALHO BATISTA, DIEGO ANT ÔNIO COSTA ARANTES, JOSÉ ALCIDES ALMEIDA ARRUDA, FELIPE PAIVA FONSECA, RICARDO ALVES MESQUITA, ELISMAURO FRANCISCO MENDONÇA, POLLIANNA MUNIZ ALVES Source Type: research