Mesenchymal Stem Cells Accelerate the Remodeling of Bladder VX2 Tumor Interstitial Microenvironment by TGF β 1-Smad Pathway

Conclusions: Under the induction of tumor microenvironment, MSCs can differentiate into myofibroblasts and then affect tumor interstitial microenvironment remodeling. This process is mediated by TGFβ1-Smad2 pathway.

Source: Journal of Cancer - December 14, 2019 Category: Cancer & Oncology Authors: Qingya Yang, Jun Chen, Yaofeng Zhu, Zhishun Xu Tags: Research Paper Source Type: research