Clinicopathological and Prognostic Significance of WW Domain Binding Protein 5 Expression in Papillary Thyroid Carcinoma.

Conclusion: The positive expression rate of WBP5 in PTC and the adjacent normal tissues was 42.75% (56/131) and 45.45% (10/22), respectively. WBP5 expression was significantly correlated with bilaterality, capsule invasion, and N-stage, and it was a favorable factor of DFS. Moreover, patients with a high WBP5 expression exhibited reduced risk of disease recurrence compared with that in patients with low WBP5 expression in the univariate analysis, whereas the multivariate analysis suggested that WBP5 was not an independent prognostic factor. Our results indicate that WBP5 might be a favorable prognosis indicator of PTC.
PMID: 31828091 [PubMed - in process]

Source: Biomed Res - December 14, 2019 Category: Research Authors: Qian Y, Pan Z, Guo Z, Ge X, Zheng G, Cao J, Huang P, Zhu X, Zhu X, Wen Q, Ge M Tags: Biomed Res Int Source Type: research