Assessment of the effect of efflux pump inhibitors on in vitro antimicrobial susceptibility of multidrug-resistant Acinetobacter baumannii

In this study, the effects of several EPIs, including carbonyl cyanide m-chlorophenylhydrazone (CCCP), phenylalanine-arginine β-naphthylamide (PAβN) and 1-(1-napthylmethyl)-piperazine (NMP), as well as drugs that may impact bacterial efflux mechanisms, such as omeprazole, verapamil, reserpine and the phenothiazines [prochlorperazine (PCPZ), chlorpromazine (CPZ) and promazine (PMZ)] on the in vitro antimicrobial susceptibility of MDR A. baumannii were assessed.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Letters to the Editor Source Type: research