Assessment of health-related quality of life in patients with cystinuria on tiopronin therapy
The objective of this study was to assess the HRQOL of patients with or without tiopronin treatment. For this cross-sectional survey, patients on tiopronin treatment were recruited through the “Thiola® Total Care Hub, ” a specialty pharmacy used to dispense tiopronin, and compared with patients not taking tiopronin (non-tiopronin group) who were identified from the Cystinuria Contact Registry at New York University School of Medicine. Consented patients responded to a survey that included questions about their experiences with kidney stones, the Wisconsin stone quality of life (WISQOL) (disease-specific) questionnaire, and the short form-36 version 2 (SF-36v2) (generic) HRQOL questionnaire. Statistical analyses included independent-samplet tests, one-way analysis of variance (ANOVA), and correlations. The survey was completed by 312 patients: 267 in the tiopronin group (144 male, 123 female; mean 49 years) and 45 in the non-tiopronin group (10 male, 35 female; mean 48 years). Both groups utilized pain medications similarly (24% overall). Patients on tiopronin had a significantly better HRQOL than patients not on tiopronin for all WISQOL domains (p
I'm a PGY-1, and with half of the year done and about 2 months of total actual EM time done, I'm noticing some pretty big recurrent problems. I was hoping to get some advice on how to deal. Firstly, I have a really bad habit of anchoring to diagnoses. Fairly often I'll get a strong bias towards whatever diagnosis seems most likely initially. The other day, a lady with history of kidney stones came in with colicky groin pain and couldn't get comfortable in any position. I got the workup... Recurrent Performance Problems
Black and Latino patients treated for kidney stones in emergency departments around the U.S. tend to get less pain-killing medication compared to whites, a new study finds.Reuters Health Information
Publication date: Available online 13 January 2020Source: Urology Case ReportsAuthor(s): Meng-Tian Liang, Chao Wang, Fa Zhang, Feng-Hai ZhouAbstractA 48-year-old man was presented in the local hospitalized where he lived because of lower back pain one month ago. Then he came to our hospital for kidney stones on the right side within horseshoe kidneys and hydronephrosis diagnosed by imaging and abdominal ultrasound. After we proceeded single standard percutaneous nephrolithotomy with holmium laser combined EMS, his stones were totally removed with little intraoperative bleeding. No eventful post-operative complications occu...
(Reuters Health) - Black and Latino patients treated for kidney stones in emergency departments around the U.S. tend to get less pain-killing medication compared to whites, a new study finds.
New research in pigs suggests that combining a hypertension drug and a glaucoma drug may take the pain out of passing a kidney stone.
CAMBRIDGE (CBS) – A new treatment could help ease the passage of kidney stones, according to researchers at MIT and Massachusetts General Hospital. Scientists said this week that muscle relaxants can reduce the contractions that cause pain when passing the stones. About 1 in 10 people will have the painful experience of kidney stones. They cause more than 500,000 emergency room visits in the United States every year. But local researchers think they’ve made a discovery that can help. They say delivering a combination of two muscle relaxants directly to the ureter, the tube that connects the kidneys and bladder,...
Researchers at MIT have identified a combination of muscle-relaxing drugs that, when administered to the ureter, eliminated pain in pigs with kidney stones. It would be the first new treatment in 40 years.
CONCLUSION: Our randomized control trial study shows that choosing the optimal position in the PCNL technique depends on the patient's conditions. If hemodynamic control matters to the anesthesiologist, the lateral position is appropriate. However, if control of pain and longer time of analgesia are important, the prone position may be preferred. PMID: 31788775 [PubMed - as supplied by publisher]
Conditions: Urolithiasis; Nephrolithotomy; Percutaneous Nephrolithotomy (PNL); Nephrostomy Tube (NT); Pain Interventions: Procedure: large-bore nephrostomy tube (LBNT); Procedure: small-bore nephrostomy tube (SBNT) Sponsor: Mansoura University Active, not recruiting