Vitamin D and depression: mechanisms, determination and application.

Vitamin D and depression: mechanisms, determination and application.
Asia Pac J Clin Nutr. 2019;28(4):689-694
Authors: Geng C, Shaikh AS, Han W, Chen D, Guo Y, Jiang P
Abstract
Depression is the most common debilitating psychiatric disease, the pathological mechanisms of which are associated with multiple aspects of neural function. While recent evidence has consistently suggested that a suboptimal vitamin D status is frequently observed in patients with depression, the results concerning whether vitamin D insufficiency is a causal factor of depression or is secondary to depressive behavior are conflicting; additionally, the lack of consistency of the method of vitamin D determination between labs has further worsened this confusion. Herein, we reviewed the neuroactivities of vitamin D that may be associated with depression and the current studies and clinical investigations to provide a full overview on the use of vitamin D in the treatment and prevention of depression.
PMID: 31826364 [PubMed - in process]

Source: Asia Pacific Journal of Clinical Nutrition - December 12, 2019 Category: Nutrition Authors: Geng C, Shaikh AS, Han W, Chen D, Guo Y, Jiang P Tags: Asia Pac J Clin Nutr Source Type: research