Aloe-emodin induces hepatotoxicity by the inhibition of multidrug resistance protein 2

ConclusionsThe inhibition of ABCC2 is a novel effect of AE that triggers oxidative stress and apoptosis. These findings are helpful in understanding the toxicological effects of AE-containing medicinal plants.Graphical Abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research