Sensing the Environment: Extracellular Lactate Levels Control Adult Neurogenesis.

Sensing the Environment: Extracellular Lactate Levels Control Adult Neurogenesis. Cell Stem Cell. 2019 Dec 05;25(6):729-731 Authors: Scandella V, Knobloch M Abstract Metabolism has emerged as a key player for stem cell behavior; however, the role of metabolism in the microenvironment remains poorly understood. In this issue of Cell Stem Cell, Wang et al. (2019) show that brain endothelial cells directly affect adult neural stem cells and maintain a healthy metabolic environment by regulating lactate levels. PMID: 31809733 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31809733?dopt=Abstract

Source: Cell Stem Cell - December 4, 2019 Category: Stem Cells Authors: Scandella V, Knobloch M Tags: Cell Stem Cell Source Type: research