Prevalence, Diagnosis and Outcomes of Treatment for Primary Aldosteronism

Publication date: Available online 5 December 2019Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): Yuhong Yang, Martin Reincke, Tracy Ann WilliamsAbstractPrimary aldosteronism (PA) is the most common potentially curable form of hypertension. The overproduction of aldosterone leads to an increased risk of cardiovascular and cerebrovascular events as well as adverse effects to the heart and kidney and psychological disorders. PA is mainly caused by unilateral aldosterone excess due to an aldosterone-producing adenoma or bilateral excess due to bilateral adrenocortical hyperplasia. The diagnostic work-up of PA comprises three steps: screening, confirmatory testing and differentiation of unilateral surgically-correctable forms from medically treated bilateral PA. These specific treatments can mitigate or reverse the increased risks associated with PA. Herein we summarise the prevalence, outcomes and current and future clinical approaches for the diagnosis of primary aldosteronism.
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research

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Source: Current Opinion in Pulmonary Medicine - Category: Respiratory Medicine Tags: GENETICS: Edited by Coline H.M. van Moorsel Source Type: research
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Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
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Source: Journal of Epidemiology - Category: Epidemiology Tags: J Epidemiol Source Type: research
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Rattus norvegicus Source Type: research
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Source: The Yale Journal of Biology and Medicine - Category: Universities & Medical Training Tags: Yale J Biol Med Source Type: research
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Drugs and Supplements Source Type: blogs
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Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
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