The Effect of Chirality on the Application of 5-[ 18 F]Fluoro-Aminosuberic Acid ([ 18 F]FASu) for Oxidative Stress Imaging

ConclusionOur data suggest that pure 2S-[18F]FASu can be used to noninvasively image system xC- in a variety of cancers, either as the racemic mixture (2S,5R/S-) or optically pure form. Furthermore, this work shows potential utility of [18F]FASu for detection of glioblastoma and prostate cancer.
Source: Molecular Imaging and Biology - Category: Molecular Biology Source Type: research