Improving patient care via development of a protein‐based diagnostic test for microbe‐specific detection of chronic rhinosinusitis

ConclusionsProteomic analysis was successful in identifying signature proteins for possible use as a biomarker for CRS. OMP‐P2 and OMP‐P5 were validated as promising candidates and were positively detected from nasopharyngeal secretions from chinchillas experimentally infected with NTHI. Collectively, these data support the use of OMP‐P2 and OMP‐P5 as biomarkers for a human clinical trial to develop a point of care medical diagnostic test to assist in the diagnosis and treatment of CRS. Level of EvidenceN/A Laryngoscope, 2013
Source: The Laryngoscope - Category: ENT & OMF Authors: Tags: Allergy/Rhinology Source Type: research