Effect of Chlorhexidine/Benzydamine Soaked Pharyngeal Packing on Throat Pain and Postoperative Nausea & Vomiting in Orthognathic Surgery

Publication date: Available online 29 November 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Çağıl Vural, Mehmet Emre Yurttutan, Kevser Tütüncüler Sancak, Ayşegül Mine TüzünerSummaryPharyngeal packing is believed to reduce postoperative nausea and vomiting (PONV) frequency, but has the disadvantage of causing throat pain. The present study aimed to investigate whether applying pharyngeal packs soaked with a combination of chlorhexidine gluconate 0.2% and benzydamine hydrochloride 0.15% (CGBH) were effective in preventing postoperative throat pain and PONV in patients undergoing orthognathic surgery. A total of 101 patients scheduled for orthognathic surgery were enrolled in this prospective, double-blind, randomized study. Patients were randomly allocated into two groups: those with CGBH-soaked packing, and those with saline-soaked pharyngeal packing. PONV was recorded using a 5-point Likert scale (0: no PONV to 4: severe PONV) immediately after the surgery at 5, 10, and 30 minutes, and at 2, 4, 6, 12, and 24 hours postoperatively. The severity of throat pain was assessed via two methods: visual analogue scale (VAS, 0: no pain, 10: severe pain) and 6-point Likert scale (0: no pain, 5: strongly severe pain) score at 2, 4, 6, 12, and 24 hours postoperatively. Mean VAS scores of throat pain were significantly lower in patients receiving CGBH-soaked pharyngeal packs compared to patients receiving saline-soaked pharyngeal packs, at all measured time point...
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research