Idiopathic Subglottic tracheal stenosis due to Gastroesophageal Reflux: Still a challenge

Conclusion: In cases of ISS where GERD is a potential causative factor, resection by endoscopy may be the treatment of choice. Once GERD is effectively treated and if symptoms are still present, one should consider tracheal resection.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring airway disease Source Type: research

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We present the case of an immunocompetent patient whose illness began at age 49 with a cough, followed by purulent and hemoptoic sputum; bronchiectasis was diagnosed. Three years later, after hemoptysis, she underwent medial segmentectomy of the middle lobe and was asymptomatic for months. When tuberculosis was found in the pathology report, she was treated with 4HREZ2R2H2. Five years later her BK was 2+, thus receiving a new scheme of 4HREZ2R2H2, which did not succeed in obtaining negative results and the treatment was declared as a failure. After genotyping her Mycobacterium intracellulare culture, the patient received a...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
This study recruited participants with a mean age of 75 years, and excluded people with symptoms or history of GERD. No placebo was used in the usual care arm. Among the primary and secondary outcomes of this review, the study only reported data on COPD exacerbations and acute respiratory infections (the common cold). As we only included one study, we could not conduct a meta-analysis. The included study reported that 12 of the 50 people on lansoprazole had at least one exacerbation over a year, compared to 26 out of 50 on usual care (risk ratio 0.46, 95% CI 0.26 to 0.81). The frequency of COPD exacerbations per person in ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Authors: Kurokawa R, Kanemitsu Y, Fukumitsu K, Takeda N, Yap JM, Suzuki M, Mori Y, Fukuda S, Uemura T, Tajiri T, Ohkubo H, Maeno K, Ito Y, Oguri T, Takemura M, Niimi A Abstract BACKGROUND: The frequency scale for the symptoms of GERD (FSSG) questionnaire, which originally consists of acid-reflux and dysmotility symptom domains, is a succinct questionnaire to evaluate gastroesophageal reflux disease (GERD) symptoms. OBJECTIVES: To evaluate the utility of subjective questionnaire of GERD for the diagnosis of GERD-related cough by using FSSG questionnaire. METHODS: We recruited 256 patients with subacute/chron...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
CONCLUSION: Prevalence of GERD in children with EA was high. Video MII-pH study to detect GERD in children with EA had high diagnostic value with the trend of specific symptom association. PMID: 32821077 [PubMed - as supplied by publisher]
Source: World Journal of Gastroenterology - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Abstract Gastro-esophageal reflux disease (GERD) patients have a higher prevalence of airway symptoms, such as chronic cough, wheezing, and hoarseness. The therapeutic management of patients with these symptoms is controversial. Therefore, this study aims to perform a systematic review and meta-analysis evaluating the efficacy of anti-reflux surgery for controlling respiratory symptoms related to GERD. A systematic review and meta-analysis was performed. Extraction of the data concerning proportions of participants who were not free of respiratory symptoms related to GERD (cough, wheezing, hoarseness) or not subst...
Source: Asian Journal of Surgery - Category: Surgery Authors: Tags: Asian J Surg Source Type: research
Patients with esophageal symptoms potentially associated with gastroesophageal reflux disease such as heartburn, regurgitation, chest pain, or cough represent one of the most frequent reasons for referral to gastroenterological evaluation. The utility of esophageal reflux monitoring in clinical practice is: (1) to accurately define reflux burden, (2) to segregate patients according to reflux monitoring results as true GERD, reflux hypersensitivity and functional heartburn, and (3) to establish a treatment plan.
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Review Article Source Type: research
1197Introduction: In this educational poster, we present three F-18 FDG (Fluorodeoxyglucose) PET/CT cases with interesting findings. First two patients had unusual presentation of diffuse large B cell lymphoma. Third patient had FDG avid lipomatous hypertrophy of interatrial septum. Findings: First Case: 51 year old man initially presented with cough, Gastroesophageal Reflux and progressive symptoms of jaundice and fatigue. He was admitted to the hospital with febrile neutropenia and CT scan showed splenomegaly as well as lymphadenopathy above and below the diaphragm. Neck mass biopsy confirmed diagnosis of diffuse B-cell ...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Oncology Poster Session (Educational Exhbits) Source Type: research
Abstract BACKGROUND: To identify esophageal sensitivity phenotypes relative to acid (SAcid), bolus (SBolus), acid and bolus (SAcid+Bolus), and none (SNone) exposures in infants suspected with gastroesophageal reflux disease (GERD). METHODS: Symptomatic infants (N = 279) were evaluated for GERD at 42 (40-45) weeks postmenstrual age using 24-h pH-impedance. Symptom-associated probability (SAP) for acid and bolus components defined esophageal sensitivity: (1) SAcid as SAP ≥ 95% for acid (pH 
Source: Pediatric Research - Category: Pediatrics Authors: Tags: Pediatr Res Source Type: research
This study aims to describe treatable traits of chronic cough and the response to pump proton inhibitor (PPI) therapy in this sub-group of patients.MethodsA retrospective, observational study was performed in patients with chronic cough in a French University Hospital. Characteristics of chronic cough were analyzed for obese (N = 112) and non-obese (N = 355) patients. Refractory cough was estimated at 6 and 12 months.ResultsThe 3 main treatable traits associated with chronic cough in obese patients and non-obese patients were gastroesophageal reflux disease (GERD), asthma, and upper airway ...
Source: Lung - Category: Respiratory Medicine Source Type: research
Authors: Griffiths TL, Nassar M, Soubani AO Abstract Introduction: Gastroesophageal Reflux Disease (GERD) is a wide spread condition with significant impact on quality of life and healthcare resources. In addition to its gastrointestinal problems, GERD is has been linked to a variety of respiratory diseases either as a direct cause, or risk factor to inability to control or worsening of the disease.Areas covered: We performed literature search in PubMed database for articles addressing GERD and pulmonary diseases. This review will discuss several different pulmonary diseases affected by GERD ranging from upper airw...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
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