Engineering distal pulmonary epithelium from induced pluripotent stem cell (iPSC)-derived alveolar cells

Conclusions: Human iPSC-derived alveolar epithelial cells can form distal lung epithelium on both rodent and human lung scaffolds, demonstrating the future potential for patient-specific lung regeneration at a transplantable scale.

Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Gilpin, S., Wu, T., Gorman, D., Zhu, L., Evangelista-Leite, D., Vedaie, M., Kotton, D., Ott, H. Tags: Mechanisms of lung injury and repair Source Type: research