Influence of Direct Thrombin Inhibitor and Low Molecular Weight Heparin on Platelet Function in Patients with Coronary Artery Disease: A Prospective Interventional Trial

ConclusionsDTI and anti-Xa drugs exert opposite effects on platelet function. A significant decrease in platelet activation through COX1 (also known as prostaglandin G/H synthase  1) was observed with enoxaparin, but no significant differences in platelet function were observed with dabigatran.Trial RegistrationClinicalTrials.gov identifier, NCT02389582.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research