Rescue of infectious Arumowot virus from cloned cDNA: Posttranslational degradation of Arumowot virus NSs protein in human cells
This study showed an establishment of the first reverse genetics for AMTV, a lack of stability of AMTV NSs proteins in human cells, and an IFN-β gene antagonist function of AMTV NSs proteins in murine cells. The AMTV can be a nonpathogen ic surrogate model for studying phleboviruses including RVFV.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Hoai J. Hallam Source Type: research
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