Travelling Together: A Unifying Pathomechanism for  ALS.

Travelling Together: A Unifying Pathomechanism for ALS. Trends Neurosci. 2019 Nov 16;: Authors: Fratta P, Birsa N, Tosolini AP, Schiavo G Abstract Axonal transport is critical for neuronal homeostasis and relies on motor complexes bound to cargoes via specific adaptors. However, the mechanisms responsible for the spatiotemporal regulation of axonal transport are not completely understood. A recent study by Liao et al. contributes to filling this gap by reporting that RNA granules 'hitchhike' on LAMP1-positive organelles using annexin A11 as a tether. PMID: 31744630 [PubMed - as supplied by publisher]
Source: Trends in Neurosciences - Category: Neuroscience Authors: Tags: Trends Neurosci Source Type: research