Evaluation of Two Methods to Isolate Schwann Cells from Murine Sciatic Nerve

ConclusionGene expression analysis of sorted cells from both methods showed successful enrichment of SC. Lineage markers such as Map1b, p75-NTR and S100b were enriched in the sorted SC population. SC sorting by eGFP expression showed improved enrichment, particularly of mature myelinating genes, although this could represent sampling of a subset of SC.
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research