Increase in Streptococcus pneumoniae serotype 3 associated parapneumonic pleural effusion/empyema after the introduction of PCV13 in Germany.

CONCLUSION: Following the introduction of PCV13 in general childhood vaccination we observed a strong emergence of serotype 3 associated PPE/PE in the German pediatric population, including a considerable number of younger children with serotype 3 vaccine breakthrough cases and failures. Future PCVs should not only cover newly emerging serotypes, but also include a more effective component against serotype 3.
PMID: 31735502 [PubMed - as supplied by publisher]

Source: Vaccine - November 13, 2019 Category: Allergy & Immunology Authors: Goettler D, Streng A, Kemmling D, Schoen C, von Kries R, Rose MA, van der Linden M, Liese JG Tags: Vaccine Source Type: research