Hearing loss but not bone-regulating hormones predicts fractures in older women —a 17-year follow-up of the Gothenburg BEDA study

ConclusionHearing loss and higher S-Ca, but not bone-regulating hormones, medication or lifestyle factors predicted incident fractures, mainly caused by falling, during 17  years of follow-up in women up to 97 years of age.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research

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Undergoing earlier menopause is a sign of a greater burden of age-related damage and dysfunction, so it should not be surprising to see that this correlates with a greater incidence of chronic disease in the years thereafter. People with a greater burden of cell and tissue damage tend to exhibit all of the manifestations of aging earlier than their less damaged peers. These variations in damage burden and consequences from individual to individual are near all the results of lifestyle choices, particularly smoking, weight, and exercise, and environmental factors such as exposure to chronic viral infection. Genetics plays o...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
Patients at risk for osteoporotic fractures can be identified through their...Read more on AuntMinnie.comRelated Reading: AI accurately detects vertebral fractures on CT AAOS: QCT finds low bone density in lumbar fusion patients 3D DEXA enhances hip fracture risk prediction USPSTF reaffirms osteoporosis screening Vertebral CAD aces detection of compression fractures
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
AbstractPurpose of ReviewRobert ( “Bob”) Genco was a member of the research team that established the Buffalo Osteoporosis and Periodontal Disease (OsteoPerio) study. Here we detail the scientific discoveries emanating from this enduring collaboration.Recent FindingsOsteoPerio is ancillary to the Women ’s Health Initiative Observational Study (WHI-OS). WHI-OS is a longitudinal study of 93,676 postmenopausal women aged 50–79 enrolled at 40 US centers (enrolled in 1993–1998). OsteoPerio enrolled 1342 women 3 years later (1997–2001) from the Buffalo WHI-OS participants to study the ass...
Source: Current Oral Health Reports - Category: Dentistry Source Type: research
AbstractHereditary hemochromatosis (HHC) is characterized by excessive intestinal iron absorption resulting in a pathological increase of iron levels. Parenchyma damage may be a consequence of iron deposition in affected organs (e.g., liver, pancreas, gonads) as well as bones and joints, leading to osteoporosis with increased fracture risk and arthropathy. Up to date, it is not known whether HHC can also be considered as a risk factor for osteonecrosis. Likewise, the underlying skeletal changes are unknown regarding, e.g., microstructural properties of bone. We aimed to study the spectrum of skeletal complications in HHC a...
Source: Calcified Tissue International - Category: Orthopaedics Source Type: research
DISCUSSION: A significant number of patients undergoing both anatomic and reverse TSA have a concurrent diagnosis of osteoporosis. Osteoporosis represents a significant independent risk factor for periprosthetic fracture and revision shoulder arthroplasty within 2 years of surgery, regardless of the type of implant. Patients with osteoporosis should be counseled on their increased risk of complications after shoulder arthroplasty. PMID: 31977612 [PubMed - in process]
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
We present salmon calcitonin (SCT) loaded Hydroxyapatite nanoparticles (HAP-NPs) for sublingual osteoporosis therapy. Surface stabilized HAP-NPs were prepared by aqueous precipitation. SCT was loaded by ionic complexation, as confirmed by FTIR. SCT-HAP-NPs exhibited high loading efficiency (~85%), average size (~100 nm), and zeta potential (~ − 25 mv). Stability of SCT was established by circular dichroism spectroscopy and HPLC analysis. Confocal laser scanning microscopy confirmed deep penetration of SCT-HAP-NPs into the mucosa with>4-fold enhancement in permeability relative to SCT solution. Subli...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Source: Epigenetics - Category: Genetics & Stem Cells Authors: Source Type: research
This study evaluated the readability and quality of online resources discussing nutrition for IBD.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Practice Management/Quality of Care/Quality Assurance Source Type: research
The objective of this study was to examine efficacy and safety of calcifediol (25(OH)D) compared to cholecalciferol (vitamin D3) and also the relationship between different formulations of alendronate and adverse reactions. METHODS: We observed a population of women diagnosed with postmenopausal osteoporosis or osteopenia treated with alendronate 70 mg weekly associated to vitamin D3 or 25(OH)D at monthly total dose of 625 µg. Data collected both at baseline (T0) and at follow-up after at least 12 months of therapy (T1) were: demographic characteristics, BMI, full medical history, lumbar T-score, femur T-score, c...
Source: Minerva Endocrinologica - Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
Publication date: March 2020Source: Journal of Functional Foods, Volume 66Author(s): Bahareh Sarmadi, Amin Ismail, Loqman Yusof, Mohd Faridz Mod YunohAbstractThe present study evaluated the impact of cocoa on skeleton of ovariectomized rats. Animals were randomized into four groups: sham (basal diet: AIN-93M Ca and P-deficient), and three ovariectomized groups: OVX (basal diet), C6 and C12 (6% and 12% cocoa powder, respectively). Urinary calcium loss was decreased in C6 but not C12, while serum insulin-like growth factor (IGF)-I increased in both cocoa groups. Improvement in bone quality and strength was observed in femur ...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
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