Subclinical thyroid dysfunction, bone mineral density, and osteoporosis in a middle-aged Korean population

ConclusionsNo apparent association was found between subclinical hypothyroidism or subclinical hyperthyroidism defined on single TSH measurement and BMD at the lumbar spine and femur in a large cohort of middle-aged men and women. Subclinical hypothyroidism was independently associated with a lower risk of osteoporosis in postmenopausal women.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research

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Authors: Fatourechi MM, Fatourechi V Abstract Subclinical thyroid dysfunction is characterized by normal levels of peripheral thyroid hormone, paired with a TSH level that is either lower than (subclinical hyperthyroidism) or higher than (subclinical hypothyroidism) the normal laboratory reference range. Slight shifts in peripheral hormone levels result in significant serum TSH changes. The exact upper limit of normal TSH and the management of subclinical hypothyroidism are still controversial. For those with TSH between high upper limit of normal and 10 mIU/L, the authors suggest selective use of thyroxine therapy...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
ConclusionsAllo-HCT survivors are at relevant risk of endocrinopathies after transplantation, providing justification for specific monitoring to individualize treatment and follow-up. Of note, classical transplant-related variables are not enough to justify the occurrence of endocrinological disfunction: a further deeper evaluation of a misdiagnosed donor-mediated autoimmune predisposition will be essential.DisclosuresBonini: Intellia Therapeutics: Research Funding.
Source: Blood - Category: Hematology Authors: Tags: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster III Source Type: research
AbstractThyroid hormones are essential for skeletal development and are important regulators of bone maintenance in adults. Childhood hypothyroidism causes delayed skeletal development, retarded linear growth and impaired bone mineral accrual. Epiphyseal dysgenesis is evidenced by classic features of stippled epiphyses on X-ray. In severe cases, post-natal growth arrest results in a complex skeletal dysplasia. Thyroid hormone replacement stimulates catch-up growth and bone maturation, but recovery may be incomplete dependent on the duration and severity of hypothyroidism prior to treatment. A severe phenotype characteristi...
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
Authors: Haddad A, Ashkenazi RI, Bitterman H, Feldhamer I, Greenberg-Dotan S, Lavi I, Batat E, Bergman I, Cohen AD, Zisman D Abstract OBJECTIVE: To investigate endocrine comorbidities in patients with psoriatic arthritis (PsA). METHODS: A retrospective, cross-sectional study was performed with the database of Clalit Health Services, the largest healthcare provider in Israel, between 2002 and 2014. Patients with PsA were identified and matched by age and sex to healthy controls. The following morbidities were analyzed: hypo/hyperthyroidism, hypo/hyperparathyroidism, hyperprolactinemia, Cushing disease, Addison d...
Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research
By: Dr. Alan Christianson When someone you know is living with hypothyroidism, it can be tempting to think that if only the doctor would prescribe an extra helping of thyroid hormone, your friend or loved one would feel so much better and would enjoy life more. And in some cases, an extra helping might be in order. In other cases, not so much. Too much thyroid hormone can actually be dangerous, which is why doctors are loathe to bump the levothyroxin dosage up an extra 25 micrograms or so for one of their patients who's still experiencing hypothyroid symptoms. Tests always come first, and there's a good reason for that....
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Have you been eating healthy, avoiding sugar, going to the gym but still struggling to lose weight? If that's the case, you might want to think about getting your thyroid checked. Your thyroid plays an important part in regulating your metabolism and can affect your ability to lose weight. So, if you find yourself struggling to squeeze into your favorite pair of jeans despite following your New Year's resolution, stop thinking it's' your fault and instead find out if something else might be going on with that small butterfly-shaped gland in front of your windpipe. Patients often seem surprised when I say there might be som...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
ConclusionsA history of periodontal disease, cemented prostheses, presences of wear facets on the prosthetic crown and full mouth rehabilitations were identified as risk indicators for peri‐implantitis. Implants’ characteristics were not related to the presence of peri‐implantitis.
Source: Clinical Oral Implants Research - Category: Dentistry Authors: Tags: Original Article Source Type: research
ConclusionsA history of periodontal disease, cemented prostheses, presences of wear facets on the prosthetic crown and full mouth rehabilitations were identified as risk indicators for peri‐implantitis. Implants’ characteristics were not related to the presence of peri‐implantitis.
Source: Clinical Oral Implants Research - Category: Dentistry Authors: Tags: Original Article Source Type: research
CONCLUSIONS: While further studies are needed, physicians should be concerned about potential levothyroxine overtreatment in elderly osteoporosis patients. PMID: 24570805 [PubMed - indexed for MEDLINE]
Source: Journal of Preventive Medicine and Public Health - Category: Global & Universal Tags: J Prev Med Public Health Source Type: research
If your heart starts pounding and skipping beats what is your first thought? For Mary M., 49, it was, “Oh No! Is this a heart attack? Is it heart arrhythmia? I know my mother has an irregular heartbeat and my grandmother died from a stroke.  Is it my turn?” So, off she went to the doctor. Her pounding heart had been waking her up at night and she was ready for the diagnosis and sat pretty calmly through the EKG test. Her mother took heart medication, exercised and watched her diet so she knew how to handle it. When the doctor returned to the room and told her “Your heart looks fine and your heart rat...
Source: Disruptive Women in Health Care - Category: Consumer Health News Authors: Tags: Women's Health Source Type: blogs
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