Advanced Training Elective in Translational Diagnostics

Advanced Training Elective in Translational Diagnostics Deadline: November 1 The Translational Diagnostics Training Elective offers pathologists-in-training hands-on exposure to how novel histopathology-based diagnostic assays are developed, from ideation to initial validation and development, concentrating on the role pathologists play in this process. This four-week elective takes place in Tucson, Arizona, under the direction of Eric E. Walk, MD, FCAP, chief medical officer of Ventana Medical Systems, and will focus on the process of translating the latest and most promising scientific discoveries and hypotheses in the fields of molecular pathology and oncology to routine diagnostic, prognostic, and companion diagnostic tests for anatomic pathologists around the world. The participant will also be exposed to the various roles pathologists can have in industry through direct interaction with the team of anatomic and molecular pathologists within the Ventana Medical &Scientific Affairs group. The overall goal is to create awareness of how pathologists, working in a product development environment, can significantly impact patient care on a global level through diagnostic innovations and personalized health care solutions. Each elective is customized to the specific interests of the recipient based on a call with Dr. Walk prior to the start of the month. Based on these interests and also project timing and availability, a schedule is created to include exposure to se...
Source: ScanGrants feed - Category: Research Authors: Source Type: funding

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Publication date: Available online 20 July 2019Source: European UrologyAuthor(s): Elise De Bleser, Barbara Alicja Jereczek-Fossa, David Pasquier, Thomas Zilli, Nicholas Van As, Shankar Siva, Andrei Fodor, Piet Dirix, Alfonso Gomez-Iturriaga, Fabio Trippa, Beatrice Detti, Gianluca Ingrosso, Luca Triggiani, Alessio Bruni, Filippo Alongi, Dries Reynders, Gert De Meerleer, Alessia Surgo, Kaoutar Loukili, Raymond MiralbellAbstractBackgroundStereotactic body radiotherapy (SBRT) and elective nodal radiotherapy (ENRT) are being investigated as metastasis-directed treatments in oligorecurrent prostate cancer (PC); however, comparat...
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: Available online 19 July 2019Source: International Journal of Surgery Case ReportsAuthor(s): Dario Iadicola, Massimo Branca, Massimo Lupo, Eugenia Maria Grutta, Stefano Mandalà, Gianfranco Cocorullo, Antonino MirabellaAbstractIntroductionTraumatic diaphragmatic injuries are rare complications resulting from a thoracic-abdominal blunt or penetrating trauma. Left-sided diaphragmatic injuries are more commonly reported in literature. Bilateral injuries are extremely rare, occurring in about 3% of the patients and just few cases reported in literature. Traumatic diaphragmatic hernias are definitely a m...
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionPrimary retoperitoneal mucinous cystadenoma is a rare clinical entity that is usually incidentally discovered. Laparoscopic excision is safe and feasible if done by an expert laparoscopic surgeon. Care should always be taken not to cause spillage of its content.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionThere is some previous caution in using a laparoscopic approach for cystic masses due to potential seeding intra-operatively, in case of fluid spillage of a possible malignant neoplasm. We show through our case that it is possible to efficiently and safely use such an approach.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionVariations in mesenchymal gastrointestinal tumors is vast, rendering diagnosis by radiology alone difficult. As such, characteristic histologic and immunostaining features are cornerstones in precise diagnosis of esophageal schwannomas. Despite being rare in incidence, symptomatic esophageal schwannoma lesions can be excised entirely, with low rate of recurrence and favorable overall outcomes.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Authors: Nzivo MM, Lwembe RM, Odari EO, Kang'ethe JM, Budambula NLM Abstract The prevalence of Human Herpes Virus type 8 (HHV-8), Human Immunodeficiency virus (HIV), and syphilis is high in Sub-Saharan Africa. Studies on HHV-8 in Kenya are few and data on its coinfection with HIV and syphilis scanty. This cross-sectional study among female sex workers (FSWs) in Malindi, Kenya, aimed to determine the prevalence of HHV-8, HIV, and syphilis mono/coinfections and identify associated risk factors. A total of 268 FSWs consented and were administered a structured questionnaire and screened for antibodies against HHV-8, HI...
Source: Interdisciplinary Perspectives on Infectious Diseases - Category: Infectious Diseases Tags: Interdiscip Perspect Infect Dis Source Type: research
Authors: Wykretowicz M, Katulska K, Zwanzig M, Krauze T, Piskorski J, Guzik P, Wykretowicz A Abstract OBJECTIVES: Left atrial fibrosis represents a substrate for atrial fibrillation (AF) and cardioembolic events. White matter hyperintensities (WMH) are commonly found on magnetic resonance imaging (MRI) and are regarded, at least partly as ischemic brain lesions. Aortic excess pressure (excessPTI) represents an extra work performed by the left ventricle and is a new risk metric associated with cardiovascular complications. The aim of our study was to assessed whether there is a correlation between the degree of LA f...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
This study included 4044 consecutive patients who underwent isolated CABG at Oslo University Hospital, Ullevål, in Oslo, Norway in the time period from 01.01.2003 to 31.12.2015. Patient data was collected retrospectively from the quality register at the department. Information on survival status was obtained from the Norwegian National Registry. Life expectancy data for the general population was gained from Statistics Norway. RESULTS: Female patients were significantly older than male patients at the time of surgery (mean age 67.0 and 63.9 years respectively, p 
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Authors: Vasudevan A, Choi JW, Feghali GA, Kluger AY, Lander SR, Tecson KM, Sathyamoorthy M, Schussler JM, Stoler RC, Vallabhan RC, Velasco CE, Yoon A, McCullough PA Abstract OBJECTIVE: Using composite endpoints and/or only first events in clinical research result in information loss and alternative statistical methods which incorporate recurrent event data exist. We compared information-loss under traditional analyses to alternative models. DESIGN: We conducted a retrospective analysis of patients who underwent percutaneous coronary intervention (Jan2010-Dec2014) and constructed Cox models for a composite endp...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Conclusion: In the treatment of patients with CTOs, successful PCI is not associated with improved long-term cardiovascular survival or reduced the risk of MACE compared with MT alone initially. PMID: 31315453 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
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