M234 management of chronic immune thrombocytopenia in a child with germline ikaros mutation
IKAROS, a transcription factor encoded by IKZF1, is crucial for B cell development. Germline IKZF1 mutations may manifest with impaired B cell function, autoimmunity, and B cell precursor acute lymphoblastic leukemia (BCP-ALL).
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: D. Groth, M. Lakkaraja, J. Ferreira, E. Feuille, J. Bassetti, S. Kaicker Source Type: research
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