In vitro synergy of echinocandins with triazoles against fluconazole-resistant Candida parapsilosis complex isolates

ConclusionThe combination of fluconazole and itraconazole with either anidulafungin or micafungin demonstrates synergistic interactions against C. parapsilosis species complex, especially against isolates with elevated MIC values. However, the use of these combinations in clinical practice and the clinical relevance of in vitro combination results remains unclear.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research