Troponin rise and poor outcome in patients with acute atrial fibrillation: rationale and criteria of selection of patients

The role of new onset atrial fibrillation (AF) as a marker of thromboembolic risk has been demonstrated in the setting of acute myocardial infarction . Thus, someone might inquire the role of acute AF in patients with abnormal troponin not fulfilling criteria of acute myocardial infarction and might question if the minor reported range of troponin I (cTn-I) values in the study population of Conti et al (from 0.15 to 7.0 ng/mL) may not be linked with a secondary ischemic mechanism, likely an imbalance between demand and supply . However, the independent predictive value of abnormal troponin for a composite of stroke, acute coronary syndrome, revascularization, and cardiovascular death is confirmed in this report and previous others. We would say that those questions covered are legitimate, well related to the article, and of major interest. In addition, some concerns may be common to other readers and need to be discussed in the point listed below.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Correspondence Source Type: research