mTOR inactivation by ROS-JNK-p53 pathway plays an essential role in Psedolaric acid B induced autophagy-dependent senescence in murine fibrosarcoma L929 cells.

In conclusion, mTOR inactivation by ROS-JNK-p53 pathway played an important role in autophagy-dependent senescence in PAB-treated L929 cells.
PMID: 23810968 [PubMed - as supplied by publisher]

Source: European Journal of Pharmacology - June 26, 2013 Category: Drugs & Pharmacology Authors: Qi M, Zhou H, Fan S, Li Z, Yao G, Tashiro SI, Onodera S, Xia M, Ikejima T Tags: Eur J Pharmacol Source Type: research