Mixed amphetamine salts-extended release for ADHD adults with cocaine use disorder
Aims: Methylphenidate has produced modest effects in treating ADHD in those with substance use disorders, and the impact of treating ADHD on reducing substance use remains unclear. To date, there have been no controlled published studies evaluating amphetamine analogues. The purpose of this 13 week double-blind, placebo-controlled, two-site trial was to evaluate the efficacy of two robust doses of mixed amphetamine salts-extended release (MAS-ER; Adderall-XR®) as a treatment for ADHD and cocaine dependence.
On October 26th, DEA National Take Back Day will once again address a crucial public safety issue. According to the National Survey on Drug Use and Health, 9.9 million Americans misuse controlled prescription drugs – and that study indicates that most of these prescription drugs were either obtained from family and friends or found in the most-neglected staple of every bathroom: the medicine cabinet. What’s the Purpose of DEA National Take Back Day? DEA National Take Back Day gives individuals the chance to dispose of their unwanted prescription drugs in a safe, judgment-free environment. Cleaning out the aver...
The goal of this work was to perform a systematic review and meta-analysis evaluating the role of exercise in improving executive function among children and adolescents with ADHD, ASD, and fetal alcohol spectrum disorders (FASD).
Children exposed to alcohol and drugs in utero often present with a multitude of mental health symptoms, including ADHD-like symptoms of inattention, hyperactivity, and impulsivity. As a clinician trying to sort through caregiver and teacher reports, it can be challenging to understand whether symptoms are consistent with the neurologic sequalae of in utero exposure alone or whether they are truly within the range of ADHD symptomatology. It can also be challenging to understand to what extent symptoms are improving or worsening with medication adjustments.
Mental health symptoms in children with neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE) and fetal alcohol spectrum disorders (FASD) present with high prevalence and morbidity, often across symptom domains (eg, ADHD-like symptoms and sleep problems). Polypharmacy is often used, but no guidelines exist regarding optimal treatment for these children. Moreover, stimulant use in these children is controversial, because their responsiveness may be different because of altered neural circuitry by prenatal alcohol exposure.
Children prenatally exposed to alcohol/drugs present with ADHD-like symptoms in up to 74 percent of cases, but reduced efficacy of stimulant medications and high prevalence of comorbid look-alike symptoms in this population limits optimal mental illness treatment. The goal of the current presentation is to propose a model for mental health care for this population based on data from our clinical cohort.
CONCLUSION: This study suggests a higher prevalence of ADHD medication use amongst the PR medical student sample compared to findings reported of US medical students, as well as a high prevalence related to nonmedical use as a means for medical students to cope with their training. The nonmedical use of stimulants in the medical school setting remains of utmost public health and clinical concern. The results of this study could help develop proper workshops and non-pharmacological techniques to help medical students cope with their workload. PMID: 31536633 [PubMed - in process]
ConclusionOur panoramic meta-overview suggests that exercise can be an effective adjunctive treatment for improving symptoms across a broad range of mental disorders.
Let’s dive into this week’s Psychology Around the Net for some perspective on how we decide to trust the news we trust, new research on a hormone we secrete when we’re panicked, a survey that shows happy people don’t just ignore the social issues around them, and more. Substance Use in the Food Service Industry: The American Addiction Centers recently conducted a survey that sheds some light on substance use among workers in the food service industry, an industry that is often stereotyped for drug and alcohol use. Among some of the findings: 10% of workers report they work while under the influence...
Conclusion/Importance: Brief screenings for ADHD, other psychiatric disorders and sexual risk behaviors can provide data for tailoring substance abuse services to improve adolescent health outcomes for high-risk subgroups. PMID: 31502500 [PubMed - as supplied by publisher]
CONCLUSION: Results of our study do not indicatea significant association between the NOS1 exon 1f-VNTR genotypes and AD, subgroups of AD, impulsiveness or comorbid ADHD semptoms. PMID: 31487373 [PubMed - in process]