Cord Plasma Biomarkers of In Utero Acetaminophen Exposure and ADHD and ASD Risk

This cohort study of mother-infant dyads examines the associations between cord plasma acetaminophen metabolites and physician-diagnosed attention-deficit/hyperactivity disorder, autism spectrum disorder, and other developmental disabilities.
Source: JAMA Psychiatry - Category: Psychiatry Source Type: research

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Authors: Biederman J, DiSalvo M, Woodworth KY, Fried R, Uchida M, Biederman I, Spencer TJ, Surman C, Faraone SV Abstract BACKGROUND.: A growing body of research suggests that deficient emotional self-regulation (DESR) is common and morbid among attention-deficit/hyperactivity disorder (ADHD) patients. The main aim of the present study was to assess whether high and low levels of DESR in adult ADHD patients can be operationalized and whether they are clinically useful. METHODS.: A total of 441 newly referred 18- to 55-year-old adults of both sexes with Diagnostic and Statistical Manual of Mental Disorders: Fifth...
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
Conclusions Early-onset neurodevelopmental dis orders, particularly with comorbidity, have a far-reaching impact on adult life in terms of SA and DP.byVirtanen M, Lallukka T, Kivim äki M, Alexanderson K, Ervasti J, Mittendorfer-Rutz E. doi:10.5271/sjweh.3885
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Tags: Original article Source Type: research
Conclusions Early-onset neurodevelopmental disorders, particularly with comorbidity, have a far-reaching impact on adult life in terms of SA and DP. PMID: 32076730 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Authors: Tags: Scand J Work Environ Health Source Type: research
Infection by the parasite Toxoplasma, which affects about 33% of world population, is associated with an increased risk of several mental health disorders, the most strongly with schizophrenia. It is unknown whether schizophrenia is associated with this infection the most strongly, or whether this association has just been the most intensively studied for historical reasons. We used the data from 6,367 subjects tested for toxoplasmosis who took part in an internet survey to search for associations of these infections with 24 mental health disorders and evidence of otherwise impaired mental health. The typical symptom assoc...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
In conclusion, school-aged children with CP very often screened positive for ASD and/or ADHD. The prevalence of ASD and ADHD is most likely underestimated in children with CP. These screening findings require further investigations.
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
In this report, we describe the prevalence and disease burden of each mental disorder for the states of India, from 1990 to 2017.MethodsWe used all accessible data from multiple sources to estimate the prevalence of mental disorders, years lived with disability (YLDs), and disability-adjusted life-years (DALYs) caused by these disorders for all the states of India from 1990 to 2017, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We assessed the heterogeneity and time trends of mental disorders across the states of India. We grouped states on the basis of their Socio-demographic Index (SDI), whi...
Source: The Lancet Psychiatry - Category: Psychiatry Source Type: research
Childhood neurodevelopmental disorders include autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), communication disorders, learning disabilities, and developmental motor coordination problems, among others (1). These conditions are typically considered to originate early in development, although there have been recent, controversial challenges to this assumption for ADHD (2). Childhood neurodevelopmental disorders, regardless of whether they are defined as diagnostic categories or traits, show strong phenotypic and genetic overlaps with each other (1).
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Commentary Source Type: research
Publication date: Available online 12 December 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Naomi Tistarelli, Corrado Fagnani, Miriam Troianiello, Maria Antonietta Stazi, Walter AdrianiAbstractAttention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children worldwide, and also the recognition of its persistence into adulthood is increasing. While ADHD in childhood is highly heritable and mostly driven by familial factors, during adulthood it appears to show a lower heritability, even if there is not total agreement on this yet. This disorder often co-occurs with many othe...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
CONCLUSION: To our knowledge, this is the first time that the child-specific health outcomes of preterm birth, low birth weight, asthma, autism spectrum disorder, attention-deficit/hyperactivity disorder, and IQ reduction have been systematically valued and presented in one place. This is an important addition to the body of health-related valuation literature as these outcomes have substantial economic costs that are not considered in most assessments of the benefits of air pollution and climate mitigation policies. In general, however, the available per-case estimates presented here did not incorporate the broad societal...
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
ConclusionThe WISC-IV profiles might help distinguishing between the cognitive characteristics of ASD and ADHD boys.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
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