Dalfampridine Improves Sensorimotor Function in Rats With Chronic Deficits After Middle Cerebral Artery Occlusion [Basic Sciences]

Conclusions— Dalfampridine improves sensorimotor function in the rat permanent middle cerebral artery occlusion model. Dalfampridine extended-release tablets (prolonged release fampridine outside the United States) are used to improve walking in patients with multiple sclerosis, and these preclinical data provide a strong rationale for examining the potential of dalfampridine to treat chronic stable deficits in stroke patients. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01605825
Source: Stroke - Category: Neurology Authors: Tags: Animal models of human disease, Other Stroke Treatment - Medical Basic Sciences Source Type: research