Study of Brain Efficacy and Reorganization After Combined Donepezil Treatment, Intensive Rehabilitation and Transcranial Direct Current Stimulation in Post-stroke Chronic Aphasia

Conditions:   Aphasia;   Stroke Interventions:   Drug: Donepezil;   Behavioral: Intensive-Language Action Therapy;   Device: Transcranial direct current stimulation Sponsor:   University of Malaga Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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(Medical University of South Carolina) Researchers at the Medical University of South Carolina (MUSC) and elsewhere report in Brain that the left lateral temporal cortex must be intact in stroke patients with aphasia if they are to have their speech entrained. In speech entrainment, stroke survivors practice fluent speech production by following along with another speaker. The efficacy of this experimental approach for certain patients with non-fluent aphasia will be assessed by an MUSC-led multi-site trial.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Conclusion: For the purpose of delirium screening in patients with aphasia, increasing the ICDSC cut-off value to ≥ 5 points enables effective screening. Further studies are necessary to characterize post-stroke delirium.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Vision, Aphasia, Neglect (VAN) is a large vessel occlusion (LVO) screening tool that was initially tested in a small study where emergency department (ED) nurses were trained to perform VAN assessment on stroke code patients. We aimed to validate the VAN assessment in a larger inpatient dataset.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
Abstract Background: Aphasia negatively impacts quality of life. This is the first Brazilian study that investigates the prevalence of aphasia and its related factors, the results of which may underpin hospital and health service planning for this vulnerable population.Objective: To establish the prevalence of aphasia in patients after first-ever ischemic stroke (FEIS) and associated factors.Methods: This is a retrospective cohort study, based on a database held in Joinville, Brazil. All cases of FEIS admitted to one public hospital in Joinville in 2015 were selected. The diagnosis of aphasia was verified by neuro...
Source: Topics in Stroke Rehabilitation - Category: Neurology Authors: Tags: Top Stroke Rehabil Source Type: research
The Vision, Aphasia, and Neglect (VAN) screening tool is a simple bedside test developed to identify patients with large vessel occlusion stroke. In the setting of intracerebral hemorrhage (ICH), there are very few bedside predictors of need for neurosurgical interventions other than age and Glasgow Coma Scale (GCS). We aimed to assess the utility of the VAN screening tool in predicting the need for neurosurgical intervention in patients with ICH.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
Conditions:   Aphasia;   Stroke Interventions:   Device: Anodal transcranial direct current stimulation;   Device: Sham transcranial direct current stimulation;   Behavioral: Speech-Language Therapy Sponsor:   Louisiana State University and A&M  College Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In conclusion, FAS is a rare motor speech disorder, often related to cerebrovascular accidents involving critical regions in the dominant hemisphere. In addition, the present case adds further evidence to the role of the left primary motor cortex in modulation of prosody. In rare cases FAS can be the only sign of stroke or can appear after recovery from post-stroke aphasia.
Source: Neurological Sciences - Category: Neurology Source Type: research
Conditions:   Aphasia;   Stroke Interventions:   Drug: Donepezil;   Behavioral: Intensive-Language Action Therapy;   Device: Transcranial direct current stimulation Sponsor:   University of Malaga Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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