CT radiomic features for predicting resectability of oesophageal squamous cell carcinoma as given by feature analysis: a case control study

Computed tomography (CT) is commonly used in all stages of oesophageal squamous cell carcinoma (SCC) management. Compared to basic CT features, CT radiomic features can objectively obtain more information abou...
Source: Cancer Imaging - Category: Radiology Authors: Tags: Research article Source Type: research

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This study assessed the risk factors of fistula based on clinical information on patients with chemoradiotherapy for T4-EC.MethodsWe retrospectively reviewed the clinical data of 59 T4-EC patients who had squamous cell carcinoma without any fistula before receiving definitive or palliative chemoradiotherapy.ResultsA fistula was observed in 18 patients (31%) throughout their clinical course. The overall survival in the fistula group was significantly shorter than that in the non-fistula group (259 vs. 346  days;p = 0.0341). The axial tumor size on computed tomography (CT) was confirmed as an independent r...
Source: Esophagus - Category: Gastroenterology Source Type: research
Conclusions: Preoperative sarcopenia is an independent risk factor for pulmonary infection after minimally invasive oesophagectomy (MIE). Evaluation of preoperative sarcopenia will thus help to prevent postoperative complications. PMID: 31372290 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
CONCLUSIONS: We conclude that high levels of intratumoral F. nucleatum have a prognostic significance for predicting poor RFS in ESCC patients. More importantly, our data indicates that higher F. nucleatum burden correlates with poor response to neoadjuvant chemotherapy, suggesting the possibility that an antibiotic intervention against this bacterium may significantly improve therapeutic response in ESCC patients. PMID: 31358543 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Clin Cancer Res Source Type: research
Publication date: Available online 28 June 2019Source: International Journal of Surgery Case ReportsAuthor(s): Adel Elkbuli, Brianna Dowd, Mark McKenney, Dessy BonevaAbstractIntroductionThe occurrence of Neuroendocrine Carcinoma (NEC) of the colon is
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We sought to evaluate the diagnostic performance of fluorine-18-fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG PET/CT) in the detection of metastatic lymph nodes by combined interpre...
Source: Cancer Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
ConclusionsLymph node recurrence frequently involved the elective nodal irradiation field, with recurrent nerve lymph nodes being common metastasis sites. The high incidence of nodal recurrence for T1b tumors with lymphovascular invasion highlights a need for new strategies for treating this subset of superficial esophageal squamous cell carcinomas.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
220Objectives: To evaluate the diagnostic performance of 18F-FDG PET/CT in detecting individual lymph node metastasis using Hounsfield units of lymph nodes on non-contrast CT image component and 18F-FDG uptake in patients with esophageal squamous cell carcinoma. Methods: 203 patients with esophageal squamous cell carcinoma underwent 18F-FDG PET/CT before esophagectomy and lymph node dissection. Maximum standardized uptake value (SUVmax), mean Hounsfield unit (HU), and short axis diameters (size) were evaluated on non-contrast CT and PET images of PET/CT scan. The images were analyzed by three methods. In Method 1, nodal st...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: GI & amp;acirc; amp;euro; ' Colorectal, Liver, Esophageal Source Type: research
Conclusions: To cover 94.5% of ESCC subclinical lesions in the CTVp, a 3-cm margin along the cranial-caudal axis should be added to the primary gross tumor volume as defined by FDG-PET/CT, as well as a cutoff SUVmax value of 2.5. Although preoperative FDG PET/CT images may not reveal lesions directly, the SUVmax and MTV measurements together could predict their presence. Background Esophageal carcinoma often occurs as squamous cell carcinoma (ESCC), a highly aggressive malignancy with a poor prognosis worldwide. The incidence rates of ESCC are particularly high in China (1). Most patients with ESCC have locally adv...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Conclusions: In OSCC, very low preoperative NLR values have a negative prognostic impact on survival and recurrence, similarly to high ratios. ENE and perineural spread are the most important clinical-pathologic prognosticators. Introduction Oral squamous cell carcinoma (OSCC) accounts for more than 95% of oral tumors and is the eighth most frequent cancer worldwide, with an estimated incidence of 640,000 new cases per year (1). Survival of OSCC has slightly improved over the last 30 years, probably as a consequence of multimodal treatment spreading. However, intensified therapeutic regimens can result in signific...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Authors: D'Journo XB Abstract Epidemiology of esophageal cancer and esophagogastric junction (EGJ) has deeply changed for the past two decades with a dramatically increase of adenocarcinoma whereas squamous cell carcinoma (SCC) has slowly decreased. Moreover, the two histological types differ in a number of features including risks factors, tumor location, tumor biology and outcomes. In acknowledgement of these differences, the newest 8th edition of the American Joint Committee on Cancer (AJCC) tumor, node and metastasis (TNM) staging classification of epithelial cancers of the esophagus and EGJ has refined this hi...
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
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