Oxaliplatin plus Capecitabine in the Perioperative Treatment of Locally Advanced Gastric Adenocarcinoma in Combination with D2 Gastrectomy: NEO‐CLASSIC Study

Conclusion.These findings suggest that combination therapy with capecitabine and oxaliplatin as perioperative chemotherapy, followed by D2 gastrectomy, is effective and safe in late‐stage, locally advanced gastric cancer. Although enrollment exceeded the 47 patients required to identify an increase in the ORR by 15% (from 40% to 55%), results did not meet the primary endpoint.

Source: The Oncologist - October 15, 2019 Category: Cancer & Oncology Authors: Yiyi Yu, Yong Fang, Zhenbin Shen, Yan Wang, Min Yan, Hui Cao, Yingbin Liu, Xuefei Wang, Yuehong Cui, Fenglin Liu, Weidong Chen, Wei Li, Qian Li, Huiqin Jiang, Yihong Sun, Tianshu Liu Tags: Chinese Edition, Clinical Trial Results, Gastrointestinal Cancer Source Type: research