Allele-specific nonstationarity in evolution of influenza A virus surface proteins [Evolution]

Influenza A virus (IAV) is a major public health problem and a pandemic threat. Its evolution is largely driven by diversifying positive selection so that relative fitness of different amino acid variants changes with time due to changes in herd immunity or genomic context, and novel amino acid variants attain...

Source: Proceedings of the National Academy of Sciences - October 14, 2019 Category: Science Authors: Anfisa V. Popova, Ksenia R. Safina, Vasily V. Ptushenko, Anastasia V. Stolyarova, Alexander V. Favorov, Alexey D. Neverov, Georgii A. Bazykin Tags: PNAS Plus Source Type: research