Tacrolimus and Indomethacin are Safe and Effective at Reducing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography in Patients Who Have Undergone Liver Transplantation

Biliary complications occur in up to 25% of patient following liver transplantation and are often managed by endoscopic retrograde cholangiopancreatography (ERCP). Pancreatitis is the most common adverse event after ERCP (PEP). Tacrolimus and rectal indomethacin have each been reported to reduce risk of PEP. We investigated the incidence of PEP in patients who have undergone ERCP after liver transplantation and the effectiveness of tacrolimus and/or indomethacin in reducing risk of PEP.

Source: Clinical Gastroenterology and Hepatology - October 13, 2019 Category: Gastroenterology Authors: Nikhil R. Thiruvengadam, Kimberly A. Forde, Vinay Chandrasekhara, Nuzhat A. Ahmad, Gregory G. Ginsberg, Vandana Khungar, Michael L. Kochman Source Type: research