The rate of myocardial perfusion recovery after steroid therapy and its implication for cardiac events in cardiac sarcoidosis and primarily preserved left ventricular ejection fraction

ConclusionsMyocardial perfusion was recovered by steroid therapy in 61% and preserved in 8% of patients. Myocardial perfusion recovery after steroid therapy was significantly associated with a low incidence of MACE.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research

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ConclusionsIdiopathic granulomatous hypophysitis, a rare inflammatory disease of the pituitary gland, is a diagnosis of exclusion for which both medical and surgical management are reported in the literature. We present a case of idiopathic granulomatous hypophysitis who was symptom free with no complications of hypopituitarism following its transsphenoidal resection after 9  months of follow-up.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
UCLA Health has launched a $20 million fundraising initiative to create a new center for advanced lung disease at theDavid Geffen School of Medicine at UCLA. To date, the initiative has secured $4.37 million for the Lung Health Research Accelerator Fund, including three gifts of $1 million each from Michael and Linda Keston, William Pierpoint, and Jeffrey and Robin Raich, and a total of $1.37 million from nine other donors.The fund will support the work of Dr. John Belperio and Dr. Joseph Lynch III in the medical school ’s division of pulmonary and critical care medicine. Belperio’s research is focused on ident...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Kaiser et al. [1] make a compelling case for T-lymphocytes in the pathogenesis of sarcoidosis, particularly when considering the initiation of granulomatous inflammation and patients with acute, self-resolving sarcoidosis (Lofgren's syndrome). However, in some situations it seems that T-cells are less important. For example, SCID (severe combined immunodeficient) mice, which have no lymphocytes, develop macrophage-rich granulomas when infected with mycobacteria [2]. In clinical practice, powerful suppression of T-lymphocytes with anti-rejection medication cannot prevent recurrence of granulomas in one third of patients who...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Correspondence Source Type: research
ConclusionTo ensure a consensus about the therapy and follow up, we have to make revisions and reorganisations on the DPLD classification which was proposed in 2007. We need a new childhood DPLD classification that will cover all these disease groups.
Source: The Clinical Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Article Source Type: research
PMID: 31729007 [PubMed - as supplied by publisher]
Source: The Australasian Journal of Dermatology - Category: Dermatology Authors: Tags: Australas J Dermatol Source Type: research
This case series study measures the responsiveness of the Cutaneous Sarcoidosis Activity and Morphology Instrument to changes in disease activity over time.
Source: JAMA Dermatology - Category: Dermatology Source Type: research
ConclusionSymptoms of pyloric obstruction as a manifestation of isolated gastric Crohn ’s disease are extremely unusual in clinical practice, awareness of which would facilitate early appropriate investigations and treatment.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Source: Journal of Medical Ultrasonics - Category: Radiology Source Type: research
Authors: Çulha G, Kaya T, Gülbol Duran G, Urhan Küçük M, Doğramacı AÇ, Tiyekli Çelik D Abstract Leishmaniasis is a parasitic disease that is transmitted to humans by the bites of infected female phlebotomine sandflies. In the diagnosis of cutaneous leishmaniasis (CL), in the smear samples, the demonstration of the parasite by microscope remains a gold standard method. However, it becomes difficult to diagnose the parasite since the number of amastigotes in chronic cases with a lesion of one year or longer is very low. Due to many factor such as patients primarily do not ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
We presented a 56-year-old woman with renal impairment who was diagnosed with sarcoidosis accompanied by IgA nephropathy. Treatment with methylprednisolone was started for the patient. After treatment, the patient was discharged with good general condition and resolved proteinuria. PMID: 31705752 [PubMed - in process]
Source: Iranian Journal of Kidney Diseases - Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research
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