Exosomes Released by Bone Marrow Mesenchymal Stem Cells Attenuate Lung Injury Induced by Intestinal Ischemia Reperfusion via the TLR4/NF- κB Pathway.

Conclusions: MSC-derived exosomes provide protection similar to that of MSCs against IIR-induced ALI via inhibition of TLR4/NF-κB signaling, suggesting that a potential strategy against IIR-mediated acute lung injury could be therapy with exosomes as a non-cellular alternative to MSC transplantation. PMID: 31588189 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31588189?dopt=Abstract

Source: International Journal of Medical Sciences - October 8, 2019 Category: Biomedical Science Tags: Int J Med Sci Source Type: research