Metformin ‐sensitized NSCLC cells to osimertinib via AMPK‐dependent autophagy inhibition

ConclusionMetformin inhibited autophagy and enhanced osimertinib sensitivity via inducing AMPK activation in a time ‐dependent manner.

Source: The Clinical Respiratory Journal - October 6, 2019 Category: Respiratory Medicine Authors: Hengyi Chen, Caiyu Lin, Conghua Lu, Yubo Wang, Rui Han, Li Li, Shuai Hao, Yong He Tags: ORIGINAL ARTICLE Source Type: research