White matter T2 hyperintensities and blood-brain barrier disruption in the hyperacute stage of subarachnoid hemorrhage in male mice: The role of lipocalin-2.

CONCLUSIONS: Subarachnoid hemorrhage causes very early BBB disruption and LCN2 expression in white matter that is associated with and may precede T2 hyperintensities. LCN2 deletion attenuates MRI changes and pathological changes in white matter after SAH. PMID: 31568658 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31568658?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - September 29, 2019 Category: Neuroscience Authors: Toyota Y, Wei J, Xi G, Keep RF, Hua Y Tags: CNS Neurosci Ther Source Type: research