A Comparison of Mobile- and Fixed-Bearing Unicompartmental Knee Arthroplasties in the Treatment of Medial Knee Osteoarthritis: A Systematic Review and Meta-analysis of 1,861 Patients

J Knee Surg DOI: 10.1055/s-0039-1697901Many studies have compared mobile-bearing (MB) and fixed-bearing (FB) unicompartmental knee arthroplasties (UKAs) in patients with unicompartmental knee osteoarthritis (OA). The present systematic review and meta-analysis examined the differences in the clinical and radiological outcomes of MB UKA and FB UKA. PubMed, EMBASE, and Cochrane databases, as well as Google Scholar were searched for relevant studies. Randomized controlled trials (RCTs) and cohort studies that compared MB UKA and FB UKA were included. The weighted mean difference in the knee scores and range of motion (ROM) as well as the summary odds ratio of postoperative mechanical axis alignment, radiolucency, revision rate, and complications were calculated in the MB UKA and FB UKA groups. Finally, 2 RCTs and 11 cohort studies that involved 1,861 patients (1,996 knees) were included. The FB UKA group showed better postoperative Knee Society score (KSS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and ROM than the MB UKA group. However, the MB UKA group had more knees with a neutral limb alignment and a lower incidence of polyethylene wear than the FB UKA group. No significant differences were observed between the groups with respect to radiolucency, revision rate, and complications, such as arthritis progression, aseptic loosening, and postoperative pain. This meta-analysis has demonstrated that both prostheses provided excellent clinical outcomes...
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Original Article Source Type: research

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The TV ad promises pain relief for knee osteoarthritis, the source of most of the 600,000 knee replacement surgeries performed in the US each year. A man in a bowling alley winces with pain. He nearly falls as he rolls a ball into the gutter. (Did I mention the arrow sticking out of his knee?) “Knee acting up again?” asks his buddy, clearly concerned. When pain pills don’t seem to help, his buddy suggests a procedure called Coolief for knee osteoarthritis. “I had it done six months ago,” says the bowling buddy. “And the best part is that it lasts up to one year.” What is Coolief? C...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Osteoarthritis Pain Management Tests and procedures Source Type: blogs
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Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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Source: Guardian Unlimited Science - Category: Science Authors: Tags: Osteoarthritis Science Medical research Health Source Type: news
We examined associations between patient (e.g., race, insurance), physician and practice factors (e.g., ownership, location) and treatment prescribed using multivariate logistic regression that accounted for complex sampling design. RESULTS: 2297 KOA-related physician visits (~67 (±4) million weighted-visits) were identified. For visits to orthopedists, PT and lifestyle recommendation rates declined (158/1000 to 88/1000 and 184/1000 to 86/1000, respectively), while NSAIDs and Narcotics prescriptions increased (132/1000 to 278/1000 and 77/1000 to 236/1000, respectively) overtime (p
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Arthritis Care Res (Hoboken) Source Type: research
Abstract INTRODUCTION: Platelet-rich plasma (PRP) is a potentially efficacious treatment for ankle osteoarthritis (OA), but its use has not been examined in high-quality studies. Systematic reviews show that PRP injections significantly decrease pain and improve function in patients with knee OA. Ankle OA is more common than hip or knee OA in the young active population; with a prevalence of 3.4%.PRP injections in ankle OA are shown to be safe and improve quality of life over time, but no randomised controlled trial has been conducted. Our randomised controlled trial will evaluate the efficacy of PRP injections fo...
Source: Pain Physician - Category: Anesthesiology Authors: Tags: BMJ Open Source Type: research
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Source: Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders - Category: Orthopaedics Tags: Clin Med Insights Arthritis Musculoskelet Disord Source Type: research
Conditions:   Osteoarthritis;   Arthritis, Rheumatoid;   Arthritis, Psoriatic Interventions:   Drug: Naltrexone;   Drug: Placebo Sponsors:   Brigham and Women's Hospital;   VA Boston Healthcare System Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Infectious diseases Source Type: blogs
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