Observation versus Immediate Re-induction for Acute Myeloid Leukemia Patients with Indeterminate Day 14 Bone Marrow Results
The benefit of immediate re-induction chemotherapy in patients with indeterminate day 14 bone marrow results ( ≤ 20% cellularity and 5%-20% blasts) remains unclear. Our retrospective analysis compared 25 patients receiving immediate re-induction to 25 patients undergoing observation for indeterminate day 14 results. We did not find a statistically significant difference in overall response rates, or surviv al outcome measures between both groups. Our findings question the utility of immediate re-induction chemotherapy and raise concern for over treatment in this patient population.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Omer Jamy, Charles Bodine, Devi Sampat, Rehan Sarmad, Awal Chadha, Pankit Vachhani, Nikolaos Papadantonakis, Antonio Di Stasi Tags: Original Study Source Type: research
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