Prevention of crystalline silica-induced inflammation by the anti-malarial hydroxychloroquine.
Conclusions: Our findings suggest that hydroxychloroquine blocks LMP and can significantly decrease cSiO2-induced toxicity in vitro. HCQ may be a promising treatment for prevention of cSiO2-induced lung damage.
PMID: 31556748 [PubMed - as supplied by publisher]
Source: Inhalation Toxicology - Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research